We strive to deliver the best value to our customers and ensure complete satisfaction for all our textbook rentals.
You can return your online books for any reason within our refund period – no questions asked.
Every order is available for express shipping, and return shipping is always free.
You'll be happy with the quality of your books (or we'll ship you another one on our dime).
You can extend your rental at any time – at the same cheap daily rental rate.
If you decide to keep the book it will never cost more than the purchase price.
As always, you have access to over 5 million titles. Plus, you can choose from 5 rental periods, so you only pay for what you’ll use. And if you ever run into trouble, our top-notch U.S. based Customer Service team is ready to help by email, chat or phone.
Supplemental materials are not guaranteed for used textbooks or rentals (access codes, DVDs, workbooks).
Making better use of clinical trials: computational decision support methods for evidence-based drug benefit-risk assessment
by:Gert van Valkenhoef
Health care policy decision makers routinely evaluate the health impact of alternative treatment options. Here benefit-risk assessment is key, consisting of weighing the favorable effects (benefits) and unfavorable effects (risks) of the alternatives. For example, before a new drug is allowed on the market, regulators evaluate its benefit-risk balance in...
Health care policy decision makers routinely evaluate the health impact of alternative treatment options. Here benefit-risk assessment is key, consisting of weighing the favorable effects (benefits) and unfavorable effects (risks) of the alternatives. For example, before a new drug is allowed on the market, regulators evaluate its benefit-risk balance in comparison to placebo or competing drugs. Ideally, benefit-risk assessments are based on the best available evidence, typically meaning randomized controlled trials. However, finding the evidence and explicitly linking it to the assessment is complicated by several factors. First, the results of clinical trials are mainly made available in text-based documents that can not be processed automatically. Second, the data from these trials must be combined into a consistent basis for benefit-risk analysis. Third, quantitative decision models are required to directly link decisions to the underlying evidence and to make trade-off decisions explicit. This thesis addresses these topics through the development of the Aggregate Data Drug Information System (ADDIS), an integrated system for decision support based on databases of structured clinical trials data. Novel algorithms are presented to automate network meta-analysis to combine clinical trials' results and multi-criteria decision models are developed to support benefit-risk assessment. ADDIS is open source software, available from http://drugis.org/
Since launching the first textbook rental site in 2006, BookRenter has never wavered from our mission to make education more affordable for all students. Every day, we focus on delivering students the best prices, the most flexible options, and the best service on earth. On March 13, 2012 BookRenter.com, Inc. formally changed its name to Rafter, Inc. We are still the same company and the same people, only our corporate name has changed.